Gut Microbiome in Obsessive Compulsive Disorder: Potential of Probiotics as an Adjuvant Therapy
نویسندگان
چکیده
The gut-brain axis concept has become an exciting area of research in psychiatry. Gastrointestinal inflammation and gut microbiome dysbiosis have been associated with mental health disorders. Obsessive-compulsive disorder (OCD) is a debilitating complex illness that cannot be completely curable, stemming from many causes risk factors. Generally, there limited on OCD its association the compared to other psychiatric conditions such as depression anxiety. This review aims provide insights into gastrointestinal OCD. Besides, role probiotics potential therapy will discussed this review. studies compiled demonstrated variations microbial composition, often lower diversity patients controls. also involved regulating immune system. Alteration certain groups bacteria could give rise manifestations symptoms patients. As approach restoring balance microbiome, serve effective solution. In vivo animal showed can potentially improve symptoms. Nevertheless, clinical trials are required determine efficacy adjuvant alleviate
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ژورنال
عنوان ژورنال: Progress in Microbes and Molecular Biology
سال: 2022
ISSN: ['2637-1049']
DOI: https://doi.org/10.36877/pmmb.a0000272